This 3D-animated disease progression was done for Pfizer to show a virtual time-lapse of a patient going from healthy Pre-cachexia, to Cachexia and Refractory Cachexia. The 3D animation artist had to meticulously capture numerous details of the patient model’s physical appearance, including changes in the head, sunken cheeks, prominent bones, bulging eyes, collarbone shape, breasts, shoulders, skin, hair, and facial features.